GP1BA

GP1BA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1GWB, 1M0Z, 1M10, 1OOK, 1P8V, 1P9A, 1QYY, 1SQ0, 1U0N, 2BP3, 3P72, 3PMH, 4C2A, 4C2B, 4CH2, 4CH8, 4MGX, 4YR6
Identifiers
Aliases	GP1BA, BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP, GPIbalpha, glycoprotein Ib platelet alpha subunit, glycoprotein Ib platelet subunit alpha
External IDs	OMIM: 606672 MGI: 1333744 HomoloGene: 143 GeneCards: GP1BA
Gene location (Human)
Chr.	Chromosome 17 (human)
End	4,935,023 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	70,532,862 bp
RNA expression pattern
	Top expressed in
	monocyte; ; lymph node; ; secondary oocyte; ; spongy bone; ; blood; ; bone marrow cells; ; tibialis anterior muscle; ; appendix; ; thymus; ; optic nerve;
	Top expressed in
	blood; ; yolk sac; ; spleen; ; morula; ; right ventricle; ; submandibular gland; ; abdominal wall; ; body of femur; ; lip; ; skeletal muscle tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase inhibitor activity; thrombin-activated receptor activity; protein binding;
Cellular component	cytoplasm; integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; cell surface; anchored component of external side of plasma membrane; extracellular exosome; extracellular space; extracellular matrix;
Biological process	blood coagulation, intrinsic pathway; hemostasis; fibrinolysis; negative regulation of protein kinase activity; cytokine-mediated signaling pathway; blood coagulation; platelet activation; cell surface receptor signaling pathway; cell adhesion; cell morphogenesis; regulation of blood coagulation; negative regulation of receptor signaling pathway via JAK-STAT; thrombin-activated receptor signaling pathway; platelet aggregation; regulation of megakaryocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	2811
	14723
	ENSG00000185245
	ENSMUSG00000050675
	P07359
	O35930
	NM_000173
	NM_010326
	NP_000164
	NP_034456
	Wikidata
View/Edit Human	View/Edit Mouse

Platelet glycoprotein Ib alpha chain also known as glycoprotein Ib (platelet), alpha polypeptide or CD42b (Cluster of Differentiation 42b), is a protein that in humans is encoded by the GP1BA gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.