GGPS1

GGPS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2Q80
Identifiers
Aliases	GGPS1, GGPPS, GGPPS1, geranylgeranyl diphosphate synthase 1, MDHLO, MUDHLOV
External IDs	OMIM: 606982 MGI: 1341724 HomoloGene: 31267 GeneCards: GGPS1
EC number	2.5.1.1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	235,344,532 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	14,238,073 bp
RNA expression pattern
	Top expressed in
	sperm; ; ganglionic eminence; ; islet of Langerhans; ; optic nerve; ; triceps brachii muscle; ; Achilles tendon; ; parotid gland; ; right ventricle; ; palpebral conjunctiva; ; corpus epididymis;
	Top expressed in
	pineal gland; ; medial ganglionic eminence; ; lateral geniculate nucleus; ; seminal vesicula; ; medial vestibular nucleus; ; mammillary body; ; internal carotid artery; ; cerebellar cortex; ; ventral tegmental area; ; yolk sac;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; farnesyltranstransferase activity; protein binding; metal ion binding; dimethylallyltranstransferase activity; geranyltranstransferase activity; identical protein binding;
Cellular component	cytoplasm; cytosol;
Biological process	cholesterol biosynthetic process; farnesyl diphosphate biosynthetic process; geranyl diphosphate biosynthetic process; geranylgeranyl diphosphate biosynthetic process; isoprenoid biosynthetic process; isoprenoid metabolic process; regulation of cholesterol biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	9453
	14593
	ENSG00000152904
	ENSMUSG00000021302
	O95749
	Q9WTN0
	NM_001037277; NM_001037278; NM_004837; NM_001371477; NM_001371478
NM_010282; NM_001331119; NM_001331176; NM_001331177; NM_001331178;
	NM_001331180
NP_001032354; NP_001032355; NP_001358406; NP_001358407; NP_004828;
	NP_001032354.1
NP_001318048; NP_001318105; NP_001318106; NP_001318107; NP_001318109;
	NP_034412
	Wikidata
View/Edit Human	View/Edit Mouse

Geranylgeranyl pyrophosphate synthase is an enzyme that in humans is encoded by the GGPS1 gene.

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