GABRR2

GABRR2
Identifiers
Aliases	GABRR2, gamma-aminobutyric acid type A receptor rho2 subunit, gamma-aminobutyric acid type A receptor subunit rho2
External IDs	OMIM: 137162 MGI: 95626 HomoloGene: 20471 GeneCards: GABRR2
Gene location (Human)
Chr.	Chromosome 6 (human)
End	89,315,299 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	33,095,865 bp
RNA expression pattern
	Top expressed in
	vena cava; ; skeletal muscle tissue; ; deltoid muscle; ; sperm; ; tibialis anterior muscle; ; spleen; ; smooth muscle tissue; ; blood; ; gastrocnemius muscle; ; lymph node;
	Top expressed in
	blood; ; superior colliculus; ; cerebellar cortex; ; superior frontal gyrus; ; skeletal muscle tissue; ; submandibular gland; ; quadriceps femoris muscle; ; meninges; ; esophagus; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chloride channel activity; extracellular ligand-gated ion channel activity; GABA-A receptor activity; ion channel activity; transmembrane signaling receptor activity; protein domain specific binding; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; GABA-A receptor complex; postsynaptic membrane; membrane; plasma membrane; synapse; integral component of plasma membrane; chloride channel complex; cell junction; neuron projection; GABA-ergic synapse;
Biological process	gamma-aminobutyric acid signaling pathway; chloride transmembrane transport; ion transport; chloride transport; signal transduction; visual perception; chemical synaptic transmission; ion transmembrane transport; regulation of membrane potential; nervous system process; regulation of postsynaptic membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	2570
	14409
	ENSG00000111886
	ENSMUSG00000023267
	P28476
	P56476
	NM_002043
	NM_008076
	NP_002034
	NP_032102
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid receptor subunit rho-2 is a protein that in humans is encoded by the GABRR2 gene.

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR2 is a member of the rho subunit family.

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