Frizzled
Frizzled is a family of atypical G protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol.
| Frizzled/Smoothened family membrane region | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Crystal structure of the cysteine-rich domain of mouse frizzled 8 (mfz8) | |||||||||
| Identifiers | |||||||||
| Symbol | Frizzled | ||||||||
| Pfam | PF01534 | ||||||||
| Pfam clan | GPCR_A | ||||||||
| InterPro | IPR000539 | ||||||||
| PROSITE | PDOC50038 | ||||||||
| TCDB | 9.A.14 | ||||||||
| OPM superfamily | 6 | ||||||||
| OPM protein | 4jkv | ||||||||
| CDD | cd13951 | ||||||||
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