FOSL1

FOSL1
Identifiers
Aliases	FOSL1, FRA, FRA1, fra-1, FOS like 1, AP-1 transcription factor subunit
External IDs	OMIM: 136515 MGI: 107179 HomoloGene: 3967 GeneCards: FOSL1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	65,900,573 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	5,505,974 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; gallbladder; ; vena cava; ; mucosa of urinary bladder; ; islet of Langerhans; ; ascending aorta; ; cervix epithelium; ; left uterine tube; ; skin of abdomen; ; upper lobe of left lung;
	Top expressed in
	supraoptic nucleus; ; lip; ; ascending aorta; ; calvaria; ; esophagus; ; stomach; ; yolk sac; ; visual cortex; ; zone of skin; ; cerebellar cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytosol; intracellular membrane-bounded organelle; neuron projection; presynaptic membrane; nucleus; nucleoplasm;
Biological process	cellular response to extracellular stimulus; response to cytokine; regulation of transcription, DNA-templated; response to organic cyclic compound; vitellogenesis; regulation of transcription by RNA polymerase II; response to progesterone; female pregnancy; response to corticosterone; response to mechanical stimulus; response to virus; positive regulation of DNA-binding transcription factor activity; placenta blood vessel development; in utero embryonic development; learning; positive regulation of DNA-templated transcription, initiation; chemotaxis; response to gravity; cellular defense response; positive regulation of cell cycle; positive regulation of cell population proliferation; positive regulation of apoptotic process; response to cAMP; response to hydrogen peroxide; positive regulation of transcription by RNA polymerase II; negative regulation of cell population proliferation; pri-miRNA transcription by RNA polymerase II; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	8061
	14283
	ENSG00000175592
	ENSMUSG00000024912
	P15407
	P48755
	NM_001300844; NM_001300855; NM_001300856; NM_001300857; NM_005438
	NM_010235
	NP_001287773; NP_001287784; NP_001287785; NP_001287786; NP_005429
	NP_034365
	Wikidata
View/Edit Human	View/Edit Mouse

Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene.

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