Flomoxef

Flomoxef is an oxacephem antibiotic that was developed by Shionogi.

Flomoxef
Clinical data
Trade namesFlumarin
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (6R,7R)-7-[[2-(Difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H18F2N6O7S2
Molar mass496.46 g·mol−1
3D model (JSmol)
Melting point82.5 to 87.5 °C (180.5 to 189.5 °F)
  • CO[C@@]1([C@@H]2N(C1=O)C(=C(CO2)CSc3nnnn3CCO)C(=O)O)NC(=O)CSC(F)F
  • InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1 N
  • Key:UHRBTBZOWWGKMK-DOMZBBRYSA-N N
 NY (what is this?)  (verify)

It has been classified either as a second-generation or fourth-generation cephalosporin.

It was patented in 1982 and approved for medical use in 1988 under the trade name Flumarin.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.