Fel d 1
Fel d 1 is a secretoglobin protein complex that, in cats, is encoded by the CH1 (chain 1/Fel d 1-A) and CH2 (chain 2/Fel d 1-B) genes.
| Allergen Fel d 1, chain 1 (P30438) | |
|---|---|
| Identifiers | |
| Symbol | Allergen_Fel_d_I_chain1 |
| InterPro | IPR006178 |
| Allergen Fel d 1, chain 2 (P30440) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Crystallographic structure of the Fel d 1 dimer, the primary allergen present in cat saliva | |||||||||
| Identifiers | |||||||||
| Symbol | Feld-I_B | ||||||||
| Pfam | PF09252 | ||||||||
| Pfam clan | CL0370 | ||||||||
| InterPro | IPR015332 | ||||||||
| SCOP2 | 1puo / SCOPe / SUPFAM | ||||||||
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Among cats, Fel d 1 is produced largely in their saliva and by the sebaceous glands located in their skin. It is the primary allergen present on cats and kittens. The function of the protein for cats is unknown, but it causes an IgG or IgE reaction in sensitive humans (either as an allergic or asthmatic response).
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