FGF9

FGF9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1G82, 1IHK
Identifiers
Aliases	FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3, fibroblast growth factor 9
External IDs	OMIM: 600921 MGI: 104723 HomoloGene: 1523 GeneCards: FGF9
Gene location (Human)
Chr.	Chromosome 13 (human)
End	21,704,498 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	58,350,177 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; renal medulla; ; Brodmann area 23; ; pons; ; cerebellar vermis; ; middle temporal gyrus; ; parietal pleura; ; germinal epithelium; ; glomerulus; ; kidney tubule;
	Top expressed in
	internal carotid artery; ; facial motor nucleus; ; pontine nuclei; ; substantia nigra; ; medial vestibular nucleus; ; lateral geniculate nucleus; ; cerebellar vermis; ; medial geniculate nucleus; ; medial dorsal nucleus; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	heparin binding; fibroblast growth factor receptor binding; protein tyrosine kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; 1-phosphatidylinositol-3-kinase activity; growth factor activity;
Cellular component	cytoplasm; extracellular region; basement membrane; extracellular exosome; extracellular space;
Biological process	eye development; positive regulation of vascular endothelial growth factor receptor signaling pathway; cell differentiation; male gonad development; chondrocyte differentiation; substantia nigra development; protein import into nucleus; positive regulation of smoothened signaling pathway; regulation of timing of cell differentiation; positive regulation of epithelial cell proliferation; lung development; positive regulation of canonical Wnt signaling pathway; negative regulation of Wnt signaling pathway; negative regulation of transcription by RNA polymerase II; male sex determination; MAPK cascade; embryonic skeletal system development; multicellular organism development; positive regulation of gene expression; positive regulation of activin receptor signaling pathway; positive regulation of cardiac muscle cell proliferation; positive regulation of mesenchymal cell proliferation; embryonic limb morphogenesis; inner ear morphogenesis; angiogenesis; osteoblast differentiation; positive regulation of cell population proliferation; lung-associated mesenchyme development; embryonic digestive tract development; positive regulation of cell division; signal transduction; positive regulation of MAPK cascade; phosphatidylinositol phosphate biosynthetic process; fibroblast growth factor receptor signaling pathway; cell-cell signaling; phosphatidylinositol-3-phosphate biosynthetic process; peptidyl-tyrosine phosphorylation; regulation of signaling receptor activity; positive regulation of protein kinase B signaling; regulation of molecular function; positive regulation of vascular associated smooth muscle cell proliferation; positive regulation of vascular associated smooth muscle cell migration; negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching;
	Sources:Amigo / QuickGO
Orthologs
	2254
	14180
	ENSG00000102678
	ENSMUSG00000021974
	P31371
	P54130
	NM_002010
	NM_013518
	NP_002001
	NP_038546
	Wikidata
View/Edit Human	View/Edit Mouse

Glia-activating factor is a protein that in humans is encoded by the FGF9 gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.