Endocardial cushions

Endocardial cushions, or atrioventricular cushions, refer to a subset of cells in the development of the heart that play a vital role in the proper formation of the heart septa.

Endocardial cushions
Interior of dorsal half of heart from a human embryo of about thirty days.
Details
Carnegie stage14
Days27
PrecursorLateral plate mesoderm
Gives rise toSeptum intermedium
Identifiers
LatinTubera endocardiaca atrioventricularia
MeSHD054089
TEcushions_by_E5.11.1.6.0.0.4 E5.11.1.6.0.0.4
Anatomical terminology

They develop on the atrioventricular canal and conotruncal region of the bulbus cordis.

During heart development, the heart starts out as a tube. As heart development continues, this tube undergoes remodeling to eventually form the four-chambered heart. The endocardial cushions are a subset of cells found in the developing heart tube that will give rise to the heart's primitive valves and septa, critical to the proper formation of a four-chambered heart.

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