Embelin

Embelin (2,5-dihydroxy-3-undecyl-1,4-benzoquinone) is a naturally occurring para-benzoquinone isolated from dried berries of Embelia ribes plants. Embelin has a wide spectrum of biological activities, including antioxidant, antitumor, anti-inflammatory, analgesic, anthelmintic, antifertility and antimicrobial. Several studies have reported antidiabetic activity of embelin Embelin treatment significantly decreased paraquat‐induced lung injury through suppressing oxidative stress, inflammatory cascade (inflammatory cytokines release), and MAPK/NF‐κB signaling pathway in paraquat‐intoxicated rats Embelin and embelin derivatives selectively inhibits 5-LOX and microsomal prostaglandin E2 synthase-1

Embelin
Names
Preferred IUPAC name
2,5-Dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
Other names
Embelic acid, Emberine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.008.164
EC Number
  • 208-979-8
KEGG
UNII
  • InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3
    Key: IRSFLDGTOHBADP-UHFFFAOYSA-N
  • CCCCCCCCCCCC1=C(C(=O)C=C(C1=O)O)O
Properties
C17H26O4
Molar mass 294.391 g·mol−1
Hazards
GHS labelling:
Warning
H361
P201, P202, P281, P308+P313, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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