ENO3

ENO3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XSX
Identifiers
Aliases	ENO3, GSD13, MSE, enolase 3
External IDs	OMIM: 131370 MGI: 95395 HomoloGene: 68215 GeneCards: ENO3
Gene location (Human)
Chr.	Chromosome 17 (human)
End	4,957,131 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	70,553,339 bp
RNA expression pattern
	Top expressed in
	biceps brachii; ; triceps brachii muscle; ; thoracic diaphragm; ; body of tongue; ; gastrocnemius muscle; ; right ventricle; ; vastus lateralis muscle; ; left ventricle; ; right lobe of liver; ; deltoid muscle;
	Top expressed in
	sternocleidomastoid muscle; ; triceps brachii muscle; ; temporal muscle; ; digastric muscle; ; vastus lateralis muscle; ; tibialis anterior muscle; ; ankle; ; gastrocnemius muscle; ; extensor digitorum longus muscle; ; intercostal muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphopyruvate hydratase activity; metal ion binding; lyase activity; magnesium ion binding; protein homodimerization activity; protein heterodimerization activity;
Cellular component	plasma membrane; phosphopyruvate hydratase complex; extracellular exosome; extracellular space; cytoplasm; cytosol; membrane;
Biological process	gluconeogenesis; glycolytic process; canonical glycolysis; human ageing; skeletal muscle tissue regeneration; substantia nigra development;
	Sources:Amigo / QuickGO
Orthologs
	2027
	13808
	ENSG00000108515
	ENSMUSG00000060600
	P13929
	P21550
	NM_001193503; NM_001976; NM_053013; NM_001374523; NM_001374524
	NM_001136062; NM_001276285; NM_007933
	NP_001180432; NP_001967; NP_443739; NP_001361452; NP_001361453
	NP_001129534; NP_001263214; NP_031959
	Wikidata
View/Edit Human	View/Edit Mouse

Enolase 3 (ENO3), more commonly known as beta-enolase (ENO-β), is an enzyme that in humans is encoded by the ENO3 gene.

This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have been associated with glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jul 2010]

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