Diminazene

Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names. It is effective against certain protozoa such as Babesia, Trypanosoma, and Cytauxzoon. The drug may also be effective against certain bacteria including Brucella and Streptococcus.

Diminazene
Clinical data
Trade namesAzidin, Berenil, Ganasag, Pirocide
Other names4,4'-(1-Triazene-1,3-diyl)bis(benzenecarboximidamide)
Routes of
administration
IM, SC
ATCvet code
Legal status
Legal status
  • Veterinary use only
Identifiers
  • 4-[2-(4-Carbamimidoylphenyl)iminohydrazinyl]benzenecarboximidamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.860
Chemical and physical data
FormulaC14H15N7
Molar mass281.323 g·mol−1
3D model (JSmol)
  • C1=CC(=CC=C1C(=N)N)N/N=N/C2=CC=C(C=C2)C(=N)N
  • InChI=1S/C14H15N7/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)(H,19,20)
  • Key:XNYZHCFCZNMTFY-UHFFFAOYSA-N

Chemically it is a di-amidine and it is formulated as its aceturate salt, diminazene aceturate.

The mechanism is not well understood; it probably inhibits DNA replication, but also has affinity to RNA.

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