Dimercaprol

Dimercaprol
	Skeletal formula and ball and stick model of dimercaprol
Clinical data
Trade names	BAL in Oil
Other names	2,3-Dimercaptopropanol; British Anti-Lewisite; 2,3-Dithiopropanol; 2,3-Dimercaptopropan-1-ol; British antilewisite
AHFS/Drugs.com	Monograph
License data	US DailyMed: Dimercaprol;
Routes of; administration	intramuscular
ATC code	V03AB09 (WHO) ;
Legal status
Legal status	US: ℞-only;
Pharmacokinetic data
Excretion	Urine
Identifiers
	IUPAC name 2,3-Bis(sulfanyl)propan-1-ol;
CAS Number	59-52-9 ;
PubChem CID	3080;
DrugBank	DB06782;
ChemSpider	2971;
UNII	0CPP32S55X;
KEGG	D00167;
ChEMBL	ChEMBL1597;
CompTox Dashboard (EPA)	DTXSID5040461 ;
ECHA InfoCard	100.000.394
Chemical and physical data
Formula	C3H8OS2
Molar mass	124.22 g·mol−1
3D model (JSmol)	Interactive image;
Density	1.239 g cm−3 g/cm3
Boiling point	393 °C (739 °F) at 2.0 kPa
	SMILES OCC(S)CS;
	InChI InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2 ; Key:WQABCVAJNWAXTE-UHFFFAOYSA-N;

Dimercaprol, also called British anti-Lewisite (BAL), is a medication used to treat acute poisoning by arsenic, mercury, gold, and lead. It may also be used for antimony, thallium, or bismuth poisoning, although the evidence for those uses is not very strong. It is given by injection into a muscle.

Common side effects include high blood pressure, pain at the site of the injection, vomiting, and fever. It is not recommended for people with peanut allergies as it is typically formulated as a suspension in peanut oil. It is unclear if use in pregnancy is safe for the baby. Dimercaprol is a chelator and works by binding with heavy metals. It has a very pungent odor.

Dimercaprol was first made during World War II. It is on the World Health Organization's List of Essential Medicines.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.