DEAD box
DEAD box proteins are involved in an assortment of metabolic processes that typically involve RNAs, but in some cases also other nucleic acids. They are highly conserved in nine motifs and can be found in most prokaryotes and eukaryotes, but not all. Many organisms, including humans, contain DEAD-box (SF2) helicases, which are involved in RNA metabolism.
DEAD/DEAH box helicase | |||||||||
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Structure of the amino terminal domain of yeast initiation factor 4A. PDB 1qva | |||||||||
Identifiers | |||||||||
Symbol | DEAD | ||||||||
Pfam | PF00270 | ||||||||
Pfam clan | CL0023 | ||||||||
InterPro | IPR011545 | ||||||||
PROSITE | PDOC00039 | ||||||||
SCOP2 | 1qva / SCOPe / SUPFAM | ||||||||
CDD | cd00268 | ||||||||
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