Cortisone acetate

Cortisone acetate
Clinical data
Trade names	Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others
Other names	Cortisone 21-acetate; 17α,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;
CAS Number	50-04-4;
PubChem CID	5745;
DrugBank	DB01380;
ChemSpider	5543;
UNII	883WKN7W8X;
KEGG	D00973;
ChEBI	CHEBI:3897;
ChEMBL	ChEMBL1650;
CompTox Dashboard (EPA)	DTXSID0022858 ;
ECHA InfoCard	100.000.006
Chemical and physical data
Formula	C23H30O6
Molar mass	402.487 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O;
	InChI InChI=1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1; Key:ITRJWOMZKQRYTA-RFZYENFJSA-N;

Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed (under prescription) in many countries throughout the world, including in the United States, the United Kingdom, and various other European countries. It is the C21 acetate ester of cortisone, and acts as a prodrug of cortisone in the body.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.