Corey–Seebach reaction
The Corey–Seebach reaction, or Seebach Umpolung is a name reaction of organic chemistry that allows for acylation by converting aldehydes into lithiated 1,3-dithianes. The lithiated 1,3-dithianes serves as an acyl anion equivalent, undergoing alkylation with electrophiles. The reaction is named in honor of its discoverers, Elias J. Corey and Dieter Seebach.
| Corey–Seebach reaction | |
|---|---|
| Named after | Elias James Corey Dieter Seebach |
| Reaction type | Coupling reaction |
| Identifiers | |
| Organic Chemistry Portal | corey-seebach-reaction |
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