Contraceptive vaginal ring

A contraceptive vaginal ring is a type of hormonal insert that is placed in the vagina for the purpose of birth control. The rings themselves utilize a plastic polymer matrix that is inlaid or embedded with contraceptive drug. This drug, often one or two hormones, is absorbed directly through the bloodstream through the cells that line the vaginal wall. Some vaginal rings contain both an estrogen and a progestin (brand names NuvaRing and Annovera), which are available in Europe and the United States. Other vaginal rings contain just progesterone (brand name Progering). The progesterone-only ring is only available in Latin America, exclusively for postpartum breastfeeding parents.

NuvaRing
NuvaRing is a flexible plastic ring with both oestrogen and progesterone.
Background
TypeHormonal
First use2001
Failure rates (first year)
Perfect use0.3 for Nuvaring%
Typical use1.5 to 9 for Nuvaring%
Usage
Duration effect4 weeks for Nuvaring, 3 months for progesterone only vaginal ring
User remindersInserted for 3 weeks and then removed for 7 days for Nuvaring
Clinic reviewAnnual
Advantages and disadvantages
STI protectionNo
WeightNo proven effect
BenefitsEasy insertion and removal

The Progering is made of silicone-elastorone with an outer diameter of 58 mm and cross-sectional diameter of 8.4 mm. Similarly, Annovera has an outer diameter of 56 mm and cross-sectional diameter of 8.4 mm. In contrast, the Nuvaring has a diameter of 54 mm with a cross-sectional diameter that measures 4 mm. The vaginal rings work as a long acting drug delivery system for varying indications, including prevention of pregnancy, improvement of dysmenorrhea and menorrhagia, lower risks of ovarian and endometrial cancers, and reduction of risk of cysts in the ovaries. Although the vaginal rings do not provide protection for sexually transmitted diseases, the rings are being assessed as a possible drug delivery system for HIV prevention.

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