Citicoline

Citicoline
Clinical data
Trade names	Neurocoline
Other names	Cytidine diphosphate choline
AHFS/Drugs.com	International Drug Names
Routes of; administration	oral
ATC code	N06BX06 (WHO) ;
Legal status
Legal status	US: OTC;
Pharmacokinetic data
Bioavailability	90% oral
Excretion	respiration (as CO2) and urine
Identifiers
	IUPAC name 5'-O-[hydroxy({hydroxy[2-(trimethylammonio)ethoxy]; phosphoryl}oxy)phosphoryl]cytidine;
CAS Number	987-78-0 ;
PubChem CID	11583971;
ChemSpider	13207 ;
UNII	536BQ2JVC7;
KEGG	D00057 ;
ChEBI	CHEBI:16436 ;
ChEMBL	ChEMBL1618340 ;
CompTox Dashboard (EPA)	DTXSID9048431 ;
ECHA InfoCard	100.012.346
Chemical and physical data
Formula	C14H27N4O11P2+
Molar mass	489.335 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[N+](C)(C)CCOP(=O)([O-])OP(=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@@H](O1)N2C=CC(N)=NC2=O;
	InChI InChI=1S/C14H26N4O11P2/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25)/t9-,11-,12-,13-/m1/s1 ; Key:RZZPDXZPRHQOCG-OJAKKHQRSA-N ;
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Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes. Citicoline is naturally occurring in the cells of human and animal tissue, in particular the organs.

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