Cefaclor

Cefaclor
Clinical data
Trade names	Biocef, Ceclor, Medacef, Distaclor, Keflor, Raniclor
AHFS/Drugs.com	Monograph
MedlinePlus	a682729
Pregnancy; category	AU: B1;
Routes of; administration	Oral
ATC code	J01DC04 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	Well absorbed, independent of food intake
Metabolism	15% to 40%
Elimination half-life	0.6 to 0.9 hours
Excretion	Renal
Identifiers
	IUPAC name (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}- 3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene- 2-carboxylic acid;
CAS Number	53994-73-3 ;
PubChem CID	51038;
DrugBank	DB00833 ;
ChemSpider	46260 ;
UNII	3Z6FS3IK0K;
KEGG	D00256 ;
ChEMBL	ChEMBL8867 ;
CompTox Dashboard (EPA)	DTXSID3022748 ;
ECHA InfoCard	100.053.536
Chemical and physical data
Formula	C15H14ClN3O4S
Molar mass	367.80 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(/Cl)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccccc3)N)C(=O)O.O;
	InChI InChI=1S/C15H14ClN3O4S.H2O/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7;/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23);1H2/t9-,10-,14-;/m1./s1 ; Key:WKJGTOYAEQDNIA-IOOZKYRYSA-N ;
	(what is this?) (verify)

Cefaclor, sold under the trade name Ceclor among others, is a second-generation cephalosporin antibiotic used to treat certain bacterial infections such as pneumonia and infections of the ear, lung, skin, throat, and urinary tract. It is also available from other manufacturers as a generic.

It was patented in 1973 and approved for medical use in 1979.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.