Vaginal yeast infection

Vaginal yeast infection, also known as candidal vulvovaginitis and vaginal thrush, is excessive growth of yeast in the vagina that results in irritation. The most common symptom is vaginal itching, which may be severe. Other symptoms include burning with urination, a thick, white vaginal discharge that typically does not smell bad, pain during sex, and redness around the vagina. Symptoms often worsen just before a woman's period.

Vaginal yeast infection
Other namesCandidal vulvovaginitis, vaginal thrush
Gram stain showing the spores and pseudohyphae of Candida albicans surrounded by round vaginal skin cells, in a case of candidal vulvovaginitis.
SpecialtyGynaecology
SymptomsVaginal itching, burning with urination, white and thick vaginal discharge, pain with sex, redness around the vagina
CausesExcessive growth of Candida
Risk factorsAntibiotics, pregnancy, diabetes, HIV/AIDS
Diagnostic methodTesting the vaginal discharge
Differential diagnosisChlamydia, gonorrhea, bacterial vaginosis
TreatmentAntifungal medication
Frequency75% of women at some point

Vaginal yeast infections are due to excessive growth of Candida. These yeast are normally present in the vagina in small numbers. Vaginal yeast infections are typically caused by the yeast species Candida albicans. Candida albicans is a common fungus often harbored in the mouth, digestive tract, or vagina without causing adverse symptoms. The causes of excessive Candida growth are not well understood, but some predisposing factors have been identified.

It is not classified as a sexually transmitted infection; however, it may occur more often in those who are frequently sexually active. Risk factors include taking antibiotics, pregnancy, diabetes, and HIV/AIDS. Tight clothing, type of underwear, and personal hygiene do not appear to be factors. Diagnosis is by testing a sample of vaginal discharge. As symptoms are similar to that of the sexually transmitted infections, chlamydia and gonorrhea, testing may be recommended.

Treatment is with an antifungal medication. This may be either as a cream such as clotrimazole or with oral medications such as fluconazole. Despite the lack of evidence, wearing cotton underwear and loose fitting clothing is often recommended as a preventive measure. Avoiding douching and scented hygiene products is also recommended. Probiotics have not been found to be useful for active infections.

Around 75% of women have at least one vaginal yeast infection at some point in their lives, while nearly half have at least two. Around 5% have more than three infections in a single year. It is the second most common cause of vaginal inflammation after bacterial vaginosis.

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