CYP2B6

CYP2B6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IBD, 3QOA, 3QU8, 3UA5, 4I91, 4RQL, 4RRT, 4ZV8
Identifiers
Aliases	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450, cytochrome P450 family 2 subfamily B member 6, Cytochrome P450 2B6
External IDs	OMIM: 123930 MGI: 88598 HomoloGene: 73894 GeneCards: CYP2B6
Gene location (Human)
Chr.	Chromosome 19 (human)
End	41,018,398 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	25,626,049 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; kidney tubule; ; metanephric glomerulus; ; kidney; ; jejunal mucosa; ; bronchial epithelial cell; ; duodenum; ; internal globus pallidus; ; rectum; ; tibialis anterior muscle;
	Top expressed in
	right lung lobe; ; duodenum; ; lacrimal gland; ; parotid gland; ; submandibular gland; ; intestinal villus; ; skin of abdomen; ; jejunum; ; trachea; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	iron ion binding; arachidonic acid epoxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; metal ion binding; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; oxidoreductase activity; steroid hydroxylase activity; monooxygenase activity;
Cellular component	organelle membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; endoplasmic reticulum; cytoplasm;
Biological process	steroid metabolic process; epoxygenase P450 pathway; cellular ketone metabolic process; xenobiotic metabolic process; organic acid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1555
	13088
	ENSG00000197408
	ENSMUSG00000030483
	P20813
	P12791
	NM_000767
	NM_009999
	NP_000758
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene. CYP2B6 is a member of the cytochrome P450 group of enzymes. Along with CYP2A6, it is involved with metabolizing nicotine, along with many other substances.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.