CXCL13

CXCL13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4ZAI, 5CBA, 5CBE
Identifiers
Aliases	CXCL13, ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13, C-X-C motif chemokine ligand 13
External IDs	OMIM: 605149 MGI: 1888499 HomoloGene: 48431 GeneCards: CXCL13
Gene location (Human)
Chr.	Chromosome 4 (human)
End	77,611,834 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	96,108,927 bp
RNA expression pattern
	Top expressed in
	spleen; ; lymph node; ; appendix; ; rectum; ; periodontal fiber; ; thymus; ; superficial temporal artery; ; gallbladder; ; pylorus; ; gums;
	Top expressed in
	spleen; ; submandibular gland; ; subcutaneous adipose tissue; ; Paneth cell; ; white adipose tissue; ; external carotid artery; ; left colon; ; internal carotid artery; ; secondary oocyte; ; trachea;
	More reference expression data
	n/a
Gene ontology
Molecular function	receptor ligand activity; CCR10 chemokine receptor binding; cytokine activity; heparin binding; CXCR3 chemokine receptor binding; chemokine activity; protein heterodimerization activity; fibroblast growth factor binding; CXCR5 chemokine receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	chemokine-mediated signaling pathway; positive regulation of cytosolic calcium ion concentration; cell-cell signaling; germinal center formation; regulation of angiogenesis; chemotaxis; endothelial cell chemotaxis to fibroblast growth factor; regulation of humoral immune response; cell surface receptor signaling pathway; response to lipopolysaccharide; regulation of cell population proliferation; defense response to bacterium; negative regulation of endothelial cell chemotaxis to fibroblast growth factor; positive regulation of T cell chemotaxis; immune response; inflammatory response; chronic inflammatory response; defense response; antimicrobial humoral immune response mediated by antimicrobial peptide; regulation of signaling receptor activity; G protein-coupled receptor signaling pathway; lymphocyte chemotaxis across high endothelial venule; positive regulation of integrin activation; positive regulation of cell-cell adhesion mediated by integrin; B cell chemotaxis; activation of GTPase activity; neutrophil chemotaxis; leukocyte chemotaxis; cellular response to lipopolysaccharide;
	Sources:Amigo / QuickGO
Orthologs
	10563
	55985
	ENSG00000156234
	ENSMUSG00000023078
	O43927
	O55038
	NM_006419; NM_001371558
	NM_018866
	NP_006410; NP_001358487
	NP_061354
	Wikidata
View/Edit Human	View/Edit Mouse

Chemokine (C-X-C motif) ligand 13 (CXCL13), also known as B lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a protein ligand that in humans is encoded by the CXCL13 gene.

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