CRYM

CRYM
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2I99
Identifiers
Aliases	CRYM, DFNA40, THBP, crystallin mu
External IDs	OMIM: 123740 MGI: 102675 HomoloGene: 1424 GeneCards: CRYM
Gene location (Human)
Chr.	Chromosome 16 (human)
End	21,303,083 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	119,801,334 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; frontal pole; ; Brodmann area 10; ; orbitofrontal cortex; ; nucleus accumbens; ; Brodmann area 9; ; caudate nucleus; ; middle temporal gyrus; ; right ventricle; ; Brodmann area 46;
	Top expressed in
	hippocampus proper; ; olfactory tubercle; ; nucleus accumbens; ; subiculum; ; lip; ; Region I of hippocampus proper; ; superior frontal gyrus; ; saccule; ; prefrontal cortex; ; hair follicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; hormone binding; protein binding; protein homodimerization activity; transcription corepressor activity; NADP binding; thyroid hormone binding; thiomorpholine-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor;
Cellular component	cytoplasm; extracellular exosome; mitochondrion; nucleus; peroxisomal matrix; cytosol;
Biological process	thyroid hormone transport; negative regulation of transcription by RNA polymerase II; sensory perception of sound; lysine catabolic process; thyroid hormone metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1428
	12971
	ENSG00000103316
	ENSMUSG00000030905
	Q14894
	O54983
	NM_001014444; NM_001888; NM_001376256
	NM_016669
	NP_001879; NP_001363185
	NP_057878
	Wikidata
View/Edit Human	View/Edit Mouse

Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.

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