BMPR1B

BMPR1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3MDY
Identifiers
Aliases	BMPR1B, ALK-6, ALK6, CDw293, AMDD, BDA1D, BDA2, bone morphogenetic protein receptor type 1B, AMD3
External IDs	OMIM: 603248 MGI: 107191 HomoloGene: 20322 GeneCards: BMPR1B
Gene location (Human)
Chr.	Chromosome 4 (human)
End	95,158,448 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	141,875,186 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; bronchial epithelial cell; ; seminal vesicula; ; entorhinal cortex; ; renal medulla; ; trigeminal ganglion; ; right uterine tube; ; external globus pallidus; ; internal globus pallidus; ; Brodmann area 23;
	Top expressed in
	cumulus cell; ; secondary oocyte; ; prostate; ; stria vascularis; ; ascending aorta; ; sclerotome; ; seminal vesicula; ; Region I of hippocampus proper; ; supraoptic nucleus; ; vein;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; metal ion binding; kinase activity; protein serine/threonine kinase activity; transmembrane receptor protein serine/threonine kinase activity; transforming growth factor beta receptor activity, type I; protein binding; SMAD binding; ATP binding; transforming growth factor beta-activated receptor activity; growth factor binding;
Cellular component	integral component of membrane; HFE-transferrin receptor complex; membrane; receptor complex; plasma membrane; integral component of plasma membrane; neuronal cell body; dendrite;
Biological process	eye development; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; skeletal system development; cell differentiation; limb morphogenesis; ovarian cumulus expansion; chondrocyte differentiation; phosphorylation; positive regulation of bone mineralization; chondrocyte development; cellular response to BMP stimulus; BMP signaling pathway; protein phosphorylation; negative regulation of chondrocyte proliferation; cartilage development; positive regulation of osteoblast differentiation; transmembrane receptor protein serine/threonine kinase signaling pathway; retina development in camera-type eye; positive regulation of cartilage development; positive regulation of chondrocyte differentiation; positive regulation of cell differentiation; ovulation cycle; camera-type eye development; inflammatory response; dorsal/ventral pattern formation; endochondral bone morphogenesis; cartilage condensation; positive regulation of transcription by RNA polymerase II; proteoglycan biosynthetic process; retinal ganglion cell axon guidance; cellular response to growth factor stimulus; transforming growth factor beta receptor signaling pathway; pattern specification process;
	Sources:Amigo / QuickGO
Orthologs
	658
	12167
	ENSG00000138696
	ENSMUSG00000052430
	O00238
	P36898
	NM_001203; NM_001256792; NM_001256793; NM_001256794
NM_001277216; NM_001277217; NM_001277218; NM_001277220; NM_007560;
	NM_001355043
	NP_001194; NP_001243721; NP_001243722; NP_001243723
NP_001264145; NP_001264146; NP_001264147; NP_001264149; NP_031586;
	NP_001341972
	Wikidata
View/Edit Human	View/Edit Mouse

Bone morphogenetic protein receptor type-1B also known as CDw293 (cluster of differentiation w293) is a protein that in humans is encoded by the BMPR1B gene.

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