CD9

CD9
Identifiers
Aliases	CD9, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29, CD9 molecule
External IDs	OMIM: 143030 MGI: 88348 HomoloGene: 20420 GeneCards: CD9
Gene location (Human)
Chr.	Chromosome 12 (human)
End	6,238,271 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	125,471,754 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; trigeminal ganglion; ; Achilles tendon; ; synovial joint; ; urethra; ; bronchial epithelial cell; ; cavity of mouth; ; palpebral conjunctiva; ; gums; ; human penis;
	Top expressed in
	right lung lobe; ; seminal vesicula; ; left lung; ; parotid gland; ; lip; ; left lung lobe; ; left colon; ; sciatic nerve; ; olfactory epithelium; ; cervix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	integrin binding; protein binding;
Cellular component	integral component of membrane; external side of plasma membrane; endocytic vesicle membrane; membrane; cell surface; plasma membrane; clathrin-coated endocytic vesicle membrane; focal adhesion; extracellular vesicle; platelet alpha granule membrane; apical plasma membrane; extracellular exosome; extracellular space; integral component of plasma membrane; extracellular region;
Biological process	negative regulation of cell population proliferation; paranodal junction assembly; platelet degranulation; cell surface receptor signaling pathway; response to water deprivation; oligodendrocyte development; receptor internalization; fusion of sperm to egg plasma membrane involved in single fertilization; cell adhesion; brain development; cellular response to low-density lipoprotein particle stimulus; single fertilization; platelet activation; negative regulation of platelet aggregation; sperm-egg recognition; myoblast fusion involved in skeletal muscle regeneration; regulation of macrophage migration;
	Sources:Amigo / QuickGO
Orthologs
	928
	12527
	ENSG00000010278
	ENSMUSG00000030342
	P21926
	P40240
	NM_001769; NM_001330312
	NM_007657
	NP_001317241; NP_001760
	NP_031683
	Wikidata
View/Edit Human	View/Edit Mouse

CD9 is a gene encoding a protein that is a member of the transmembrane 4 superfamily also known as the tetraspanin family. It is a cell surface glycoprotein that consists of four transmembrane regions and has two extracellular loops that contain disulfide bonds which are conserved throughout the tetraspanin family. Also containing distinct palmitoylation sites that allows CD9 to interact with lipids and other proteins.

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