Glycoprotein IX

GP9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3REZ
Identifiers
Aliases	GP9, CD42a, GPIX, Glycoprotein IX, glycoprotein IX platelet
External IDs	OMIM: 173515 MGI: 1860137 HomoloGene: 144 GeneCards: GP9
Gene location (Human)
Chr.	Chromosome 3 (human)
End	129,062,406 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	87,756,750 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; right lung; ; spleen; ; bone marrow; ; upper lobe of left lung; ; bone marrow cells; ; placenta; ; embryo; ; right uterine tube;
	Top expressed in
	blood; ; spleen; ; morula; ; yolk sac; ; right lung; ; right lung lobe; ; abdominal wall; ; femur; ; bone marrow; ; ascending aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	platelet activation; blood coagulation, intrinsic pathway; hemostasis; cell adhesion; blood coagulation;
	Sources:Amigo / QuickGO
Orthologs
	2815
	54368
	ENSG00000169704
	ENSMUSG00000030054
	P14770
	O88186
	NM_000174
	NM_018762
	NP_000165
	NP_061232
	Wikidata
View/Edit Human	View/Edit Mouse

Glycoprotein IX (platelet) (GP9) also known as CD42a (Cluster of Differentiation 42a), is a human gene.

Platelet glycoprotein IX (GP9) is a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib (GP Ib), a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor (VWF; MIM 193400) (known as the Glycoprotein Ib-IX-V Receptor Complex). The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with GP9 and platelet glycoprotein V (GP5; MIM 173511).[supplied by OMIM]

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