F11 receptor

F11R
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1NBQ, 3EOY, 3TSZ, 4ODB
Identifiers
Aliases	F11R, F11r, 9130004G24, AA638916, ESTM33, JAM, JAM-1, JAM-A, Jcam, Jcam1, Ly106, CD321, JAM1, JAMA, KAT, PAM-1, F11 receptor
External IDs	OMIM: 605721 MGI: 1321398 HomoloGene: 14255 GeneCards: F11R
Gene location (Human)
Chr.	Chromosome 1 (human)
End	161,021,343 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	171,292,171 bp
RNA expression pattern
	Top expressed in
	right lung; ; rectum; ; islet of Langerhans; ; upper lobe of left lung; ; minor salivary gland; ; gallbladder; ; skin of abdomen; ; left lobe of thyroid gland; ; body of pancreas; ; right uterine tube;
	Top expressed in
	saccule; ; otic placode; ; corneal stroma; ; left lung lobe; ; epithelium of stomach; ; large intestine; ; colon; ; left colon; ; duodenum; ; jejunum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	PDZ domain binding; virus receptor activity; protein binding; cadherin binding;
Cellular component	integral component of membrane; membrane; cell-cell junction; bicellular tight junction; plasma membrane; slit diaphragm; extracellular exosome; cytoplasmic vesicle; cell junction;
Biological process	regulation of actin cytoskeleton reorganization; cell differentiation; establishment of endothelial intestinal barrier; epithelial cell differentiation; actomyosin structure organization; extracellular matrix organization; regulation of membrane permeability; regulation of cytokine production; positive regulation of GTPase activity; positive regulation of blood pressure; cell adhesion; negative regulation of GTPase activity; bicellular tight junction assembly; viral entry into host cell; intestinal absorption; response to radiation; inflammatory response; viral process; transforming growth factor beta receptor signaling pathway; leukocyte migration; protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	50848
	16456
	ENSG00000158769
	ENSMUSG00000038235
	Q9Y624
	O88792
NM_016946; NM_144501; NM_144502; NM_144503; NM_144504;
	NM_001348091; NM_001382727; NM_001382730; NM_001382733; NM_001382734
	NM_172647
NP_058642; NP_001335020; NP_001369656; NP_001369659; NP_001369662;
	NP_001369663
	NP_766235
	Wikidata
View/Edit Human	View/Edit Mouse

Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. It has also been designated as CD321 (cluster of differentiation 321).

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