CD31

PECAM1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KY5, 5C14
Identifiers
Aliases	PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet and endothelial cell adhesion molecule 1, PCAM-1
External IDs	OMIM: 173445 MGI: 97537 HomoloGene: 47925 GeneCards: PECAM1
Gene location (Human)
Chr.	Chromosome 17 (human)
End	64,413,776 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	106,641,454 bp
RNA expression pattern
	Top expressed in
	visceral pleura; ; lower lobe of lung; ; pericardium; ; right lung; ; parietal pleura; ; monocyte; ; upper lobe of lung; ; upper lobe of left lung; ; Achilles tendon; ; bone marrow cells;
	Top expressed in
	right lung lobe; ; left lung; ; left lung lobe; ; ascending aorta; ; aortic valve; ; glomerular capillary; ; digastric muscle; ; dermis; ; body of femur; ; soleus muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein homodimerization activity;
Cellular component	integral component of membrane; platelet alpha granule membrane; membrane raft; cell junction; plasma membrane; extracellular exosome; membrane; extracellular space; secretory granule membrane; cytoplasm; external side of plasma membrane; smooth muscle contractile fiber; cell-cell contact zone; cell periphery;
Biological process	diapedesis; glomerular endothelium development; platelet degranulation; cell adhesion; extracellular matrix organization; cell recognition; leukocyte migration; signal transduction; phagocytosis; neutrophil degranulation; leukocyte cell-cell adhesion; neutrophil extravasation; cell-cell adhesion via plasma-membrane adhesion molecules; angiogenesis; endothelial cell morphogenesis; homophilic cell adhesion via plasma membrane adhesion molecules; Rho protein signal transduction; regulation of cell migration; monocyte extravasation; wound healing; positive regulation of tyrosine phosphorylation of STAT protein; endothelial cell migration; endothelial cell-matrix adhesion;
	Sources:Amigo / QuickGO
Orthologs
	5175
	18613
	ENSG00000261371
	ENSMUSG00000020717
	P16284
	Q08481
	NM_000442
	NM_001032378; NM_008816; NM_001305157; NM_001305158
	NP_000433
	NP_001027550; NP_001292086; NP_001292087; NP_032842
	Wikidata
View/Edit Human	View/Edit Mouse

Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome17q23.3. PECAM-1 plays a key role in removing aged neutrophils from the body.

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