CD300A

CD300A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2Q87
Identifiers
Aliases	CD300A, CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60, CD300a molecule
External IDs	OMIM: 606790 MGI: 2443411 HomoloGene: 48514 GeneCards: CD300A
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,484,794 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; spleen; ; bone marrow; ; bone marrow cells; ; amniotic fluid; ; appendix; ; periodontal fiber; ; lymph node; ; spongy bone;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	signaling receptor activity; phosphatidylethanolamine binding; phosphatidylserine binding; protein binding;
Cellular component	integral component of membrane; extracellular exosome; membrane; plasma membrane; tertiary granule membrane; ficolin-1-rich granule membrane;
Biological process	regulation of T cell receptor signaling pathway; immune system process; negative regulation of eosinophil migration; positive regulation of phosphoprotein phosphatase activity; negative regulation of neutrophil activation; negative regulation of eosinophil activation; regulation of immune response; negative regulation of fibroblast proliferation; negative regulation of MAP kinase activity; negative regulation of mast cell degranulation; negative regulation of mast cell activation involved in immune response; cell adhesion; negative regulation of NK T cell activation; negative regulation of B cell receptor signaling pathway; negative regulation of activation of Janus kinase activity; negative regulation of phagocytosis, engulfment; negative regulation of B cell proliferation; signal transduction; negative regulation of MyD88-dependent toll-like receptor signaling pathway; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	11314
	217303
	ENSG00000167851
	n/a
	Q9UGN4
	Q6SJQ0
	NM_001256841; NM_007261; NM_001330456; NM_001330457
	NM_170758; NM_001347654; NM_001359812
	NP_001243770; NP_001317385; NP_001317386; NP_009192
	NP_001334583; NP_739564; NP_001346741
	Wikidata
View/Edit Human	View/Edit Mouse

CD300A (Cluster of Differentiation 300A) is a human gene.

The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998).[supplied by OMIM]

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