CD2

CD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1CDB, 1GYA, 1HNF, 1L2Z, 1QA9, 2J6O, 2J7I
Identifiers
Aliases	CD2, LFA-2, SRBC, T11, CD2 molecule
External IDs	OMIM: 186990 MGI: 88320 HomoloGene: 1338 GeneCards: CD2
Gene location (Human)
Chr.	Chromosome 1 (human)
End	116,769,229 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	101,195,255 bp
RNA expression pattern
	Top expressed in
	thymus; ; lymph node; ; appendix; ; blood; ; superficial temporal artery; ; spleen; ; jejunal mucosa; ; gallbladder; ; palpebral conjunctiva; ; rectum;
	Top expressed in
	thymus; ; spleen; ; blood; ; right lung lobe; ; subcutaneous adipose tissue; ; ankle joint; ; white adipose tissue; ; mammary gland; ; spermatid; ; bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; protein binding; signaling receptor binding; signaling receptor activity; antigen binding; protein kinase binding; receptor tyrosine kinase binding; protein self-association;
Cellular component	integral component of membrane; membrane; cell-cell junction; anchored component of plasma membrane; integral component of plasma membrane; extracellular region; cell surface; cytoplasmic side of plasma membrane; external side of plasma membrane; plasma membrane; protein-containing complex; membrane raft;
Biological process	positive regulation of myeloid dendritic cell activation; heterotypic cell-cell adhesion; natural killer cell activation; membrane raft polarization; cell surface receptor signaling pathway; cell adhesion; positive regulation of tumor necrosis factor production; T cell activation; leukocyte migration; regulation of T cell differentiation; apoptotic process; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	914
	12481
	ENSG00000116824
	ENSMUSG00000027863
	P06729; Q53F96
	P08920
	NM_001767; NM_001328609
	NM_013486
	NP_001315538; NP_001758; NP_001758.2
	NP_038514
	Wikidata
View/Edit Human	View/Edit Mouse

CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor.

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