CD1D

CD1D
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4WO4, 1ZT4, 2PO6, 3HUJ, 3SDX, 3TZV, 3U0P, 3VWJ, 3VWK, 4EN3, 4LHU, 4MNG, 4MQ7, 4WW2
Identifiers
Aliases	CD1D, CD1A, R3, R3G1, CD1d molecule
External IDs	OMIM: 188410 MGI: 107674 HomoloGene: 1337 GeneCards: CD1D
Gene location (Human)
Chr.	Chromosome 1 (human)
End	158,186,427 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	86,906,748 bp
RNA expression pattern
	Top expressed in
	monocyte; ; thymus; ; spleen; ; blood; ; right lobe of liver; ; appendix; ; jejunal mucosa; ; duodenum; ; rectum; ; bone marrow;
	Top expressed in
	white adipose tissue; ; left lobe of liver; ; subcutaneous adipose tissue; ; brown adipose tissue; ; intercostal muscle; ; body of femur; ; fossa; ; spleen; ; medial ganglionic eminence; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	beta-2-microglobulin binding; lipopeptide binding; histone binding; endogenous lipid antigen binding; lipid antigen binding; exogenous lipid antigen binding; cell adhesion molecule binding; protein binding;
Cellular component	cytoplasm; integral component of membrane; endosome; endoplasmic reticulum membrane; membrane; integral component of plasma membrane; cell surface; lysosomal membrane; basolateral plasma membrane; lysosome; endosome membrane; plasma membrane; endoplasmic reticulum; extracellular space; external side of plasma membrane;
Biological process	immune system process; T cell selection; heterotypic cell-cell adhesion; positive regulation of T cell proliferation; detection of bacterium; positive regulation of innate immune response; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; innate immune response; viral process; antigen processing and presentation, endogenous lipid antigen via MHC class Ib; regulation of immune response; positive regulation of T cell mediated cytotoxicity; immune response;
	Sources:Amigo / QuickGO
Orthologs
	912
	12479
	ENSG00000158473
	ENSMUSG00000028076
	P15813
	P11609
	NM_001766; NM_001319145; NM_001371761; NM_001371762; NM_001371763
	NM_007639; NM_001379501; NM_001379502; NM_001379503
	NP_001306074; NP_001757; NP_001358690; NP_001358691; NP_001358692
	NP_031665; NP_001366430; NP_001366431; NP_001366432
	Wikidata
View/Edit Human	View/Edit Mouse

CD1D is the human gene that encodes the protein CD1d, a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of lipid antigens to T cells. CD1d is the only member of the group 2 CD1 molecules.

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