CCR1

CCR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Y5D
Identifiers
Aliases	CCR1, CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1, C-C motif chemokine receptor 1
External IDs	OMIM: 601159 MGI: 104618 HomoloGene: 20344 GeneCards: CCR1
Gene location (Human)
Chr.	Chromosome 3 (human)
End	46,208,313 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	123,768,729 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; periodontal fiber; ; appendix; ; spleen; ; bone marrow; ; spongy bone; ; synovial membrane; ; right ventricle; ; bone marrow cells;
	Top expressed in
	blood; ; ankle; ; body of femur; ; spleen; ; ankle joint; ; duodenum; ; right lung lobe; ; ileum; ; white adipose tissue; ; dermis;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	C-C chemokine binding; G protein-coupled receptor activity; chemokine (C-C motif) ligand 5 binding; signal transducer activity; chemokine (C-C motif) ligand 7 binding; protein binding; chemokine receptor activity; C-C chemokine receptor activity; phosphatidylinositol phospholipase C activity; chemokine binding;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; external side of plasma membrane; cytoplasm;
Biological process	negative regulation of bone mineralization; positive regulation of cell migration; positive regulation of cytosolic calcium ion concentration; chemokine-mediated signaling pathway; cell-cell signaling; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; positive regulation of monocyte chemotaxis; cellular calcium ion homeostasis; positive regulation of osteoclast differentiation; dendritic cell chemotaxis; negative regulation of gene expression; chemotaxis; cell surface receptor signaling pathway; cell adhesion; response to wounding; immune response; positive regulation of ERK1 and ERK2 cascade; inflammatory response; calcium ion transport; signal transduction; exocytosis; positive regulation of calcium ion transport; G protein-coupled receptor signaling pathway; cytokine-mediated signaling pathway; calcium-mediated signaling; cell chemotaxis;
	Sources:Amigo / QuickGO
Orthologs
	1230
	12768
	ENSG00000163823
	ENSMUSG00000025804
	P32246
	P51675
	NM_001295
	NM_009912
	NP_001286
	NP_034042
	Wikidata
View/Edit Human	View/Edit Mouse

C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene.

CCR1 has also recently been designated CD191 (cluster of differentiation 191).

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