Interleukin 1 receptor, type II

IL1R2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3O4O
Identifiers
Aliases	IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, Interleukin 1 receptor, type II, interleukin 1 receptor type 2
External IDs	OMIM: 147811 MGI: 96546 HomoloGene: 7783 GeneCards: IL1R2
Gene location (Human)
Chr.	Chromosome 2 (human)
End	102,028,544 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	40,164,391 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; blood; ; right lung; ; human penis; ; cavity of mouth; ; vulva; ; periodontal fiber; ; spleen; ; rectum; ; nipple;
	Top expressed in
	esophagus; ; lip; ; skin of back; ; subcutaneous adipose tissue; ; skin of abdomen; ; cervix; ; blood; ; secondary oocyte; ; belly cord; ; bone marrow;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	interleukin-1, type II, blocking receptor activity; protein binding; interleukin-1 receptor activity; interleukin-1 binding;
Cellular component	integral component of membrane; extracellular region; plasma membrane; membrane; cytoplasm;
Biological process	immune response; negative regulation of protein processing; negative regulation of cytokine production involved in inflammatory response; negative regulation of interleukin-1-mediated signaling pathway; cytokine-mediated signaling pathway; interleukin-1-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7850
	16178
	ENSG00000115590
	ENSMUSG00000026073
	P27930
	P27931
	NM_001261419; NM_004633; NM_173343
	NM_010555; NM_001360800; NM_001360801
	NP_001248348; NP_004624
	NP_034685; NP_001347729; NP_001347730
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin 1 receptor, type II (IL-1R2) also known as CD121b (Cluster of Differentiation 121b) is an interleukin receptor. IL1R2 also denotes its human gene.

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