Mucin-16

MUC16
Identifiers
Aliases	MUC16, CA125, mucin 16, cell surface associated
External IDs	OMIM: 606154 HomoloGene: 133291 GeneCards: MUC16
Gene location (Human)
Chr.	Chromosome 19 (human)
End	8,981,342 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; palpebral conjunctiva; ; trachea; ; right uterine tube; ; minor salivary gland; ; germinal epithelium; ; endometrium; ; left uterine tube; ; parietal pleura; ; canal of the cervix;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	Golgi lumen; integral component of membrane; extracellular region; vesicle; extracellular exosome; membrane; extrinsic component of membrane; extracellular space; plasma membrane;
Biological process	cell adhesion; O-glycan processing; stimulatory C-type lectin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	94025
	n/a
	ENSG00000181143
	n/a
	Q8WXI7
	n/a
	NM_024690; NM_001401501
	n/a
	NP_078966
	n/a
	Wikidata
View/Edit Human

Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins. MUC-16 has found application as a tumor marker or biomarker that may be elevated in the blood of some patients with specific types of cancers, most notably ovarian cancer, or other conditions that are benign.

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