Binucleated cells
Binucleated cells are cells that contain two nuclei. This type of cell is most commonly found in cancer cells and may arise from a variety of causes. Binucleation can be easily visualized through staining and microscopy. In general, binucleation has negative effects on cell viability and subsequent mitosis.
Binucleated cells | |
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A binucleated cell has two nuclei. The cell above was stained with DAPI to highlight the nuclei and treated with antibodies against tubulin to highlight the microtubules to show the binucleation. | |
Specialty | Pathology |
They also occur physiologically in hepatocytes, chondrocytes and in fungi (dikaryon).
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