bZIP domain
The Basic Leucine Zipper Domain (bZIP domain) is found in many DNA binding eukaryotic proteins. One part of the domain contains a region that mediates sequence specific DNA binding properties and the leucine zipper that is required to hold together (dimerize) two DNA binding regions. The DNA binding region comprises a number of basic amino acids such as arginine and lysine. Proteins containing this domain are transcription factors.
| bZIP transcription factor | |||||||||
|---|---|---|---|---|---|---|---|---|---|
CREB (top) is a transcription factor capable of binding DNA via the bZIP domain (bottom) and regulating gene expression. | |||||||||
| Identifiers | |||||||||
| Symbol | bZIP_1 | ||||||||
| Pfam | PF00170 | ||||||||
| InterPro | IPR011616 | ||||||||
| PROSITE | PDOC00036 | ||||||||
| SCOP2 | 1ysa / SCOPe / SUPFAM | ||||||||
| CDD | cd14686 | ||||||||
| Membranome | 235 | ||||||||
| |||||||||
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.