Appalachian Development Highway System

The Appalachian Development Highway System (ADHS) is a series of highway corridors in the Appalachia region of the eastern United States. The routes are designed as local and regional routes for improving economic development in the historically isolated region. It was established as part of the Appalachian Regional Development Act of 1965, and has been repeatedly supplemented by various federal and state legislative and regulatory actions. The system consists of a mixture of state, U.S., and Interstate routes. The routes are formally designated as "corridors" and assigned a letter. Signage of these corridors varies from place to place, but where signed are often done so with a distinctive blue-colored sign.

A 2019 study found that the construction of the ADHS led to economic net gains of $54 billion (approximately 0.4 percent of national income) and boosted incomes in the Appalachian region by reducing the costs of trade.