Antennapedia

Antennapedia (abbreviated Antp) is a Hox gene first discovered in Drosophila which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae. By contrast gain-of-function alleles convert antennae into ectopic legs.

Homeotic protein antennapedia
Identifiers
OrganismDrosophila melanogaster
Symbolantp
UniProtP02833
Search for
StructuresSwiss-model
DomainsInterPro

This is just one illustration of the tendency of organisms to exhibit variations on a theme: modulated repetition. Legs and antennae are related to one another as much as molars are to incisors, fingers are to toes, and arms are to legs.

Antp also refers to a gene complex (ANT-C) in Drosophila ending with the Antp gene. It is responsible for formation and differentiation of the thoracic and head segments of the fly's body.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.