Aneurysmal bone cyst

Aneurysmal bone cyst (ABC) is a non-cancerous bone tumor composed of multiple varying sizes of spaces in a bone which are filled with blood. The term is a misnomer, as the lesion is neither an aneurysm nor a cyst. It generally presents with pain and swelling in the affected bone. Pressure on neighbouring tissues may cause compression effects such as neurological symptoms.

Aneurysmal bone cyst
Other namesNot recommended: Giant cell reparative granuloma of small bone, giant cell lesion of small bones
A. X-ray: osteolytic lesion in tibia near knee. B/C/D/E. MRI with E showing fluid levels.
SpecialtyOrthopedics
SymptomsPain, swelling, pressure related neurological symptoms
CausesUnknown
Diagnostic methodMedical imaging: CT scan, X-ray, MRI, bone scan.
Differential diagnosisTelangiectatic osteosarcoma
TreatmentSurgery
Prognosis20-70% recur after curettage.
FrequencyRare, ~0.15 cases per one million per year. 80% age <20 years. M=F

The cause is unknown. Diagnosis involves medical imaging. CT scan and X-ray show lytic expansion lesions with clear borders. MRI reveals fluid levels.

Treatment is usually by curettage, bone grafting or surgically removing the part of bone. 20–30% may recur, usually in the first couple of years after treatment, particularly in children.

It is rare. The incidence is around 0.15 cases per one million per year. Aneurysmal bone cyst was first described by Jaffe and Lichtenstein in 1942.

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