Aflibercept

Aflibercept, sold under the brand names Eylea among others, is a medication used to treat wet macular degeneration and metastatic colorectal cancer. It was developed by Regeneron Pharmaceuticals and is approved in the United States and the European Union.

Aflibercept
Clinical data
Trade namesEylea, Zaltrap
Other namesziv-aflibercept
BiosimilarsYesafili
AHFS/Drugs.comAflibercept Monograph
Ziv-aflibercept Monograph
MedlinePlusa612004
License data
Pregnancy
category
  • AU: D
  • Not recommended
Routes of
administration		Intravenous, intravitreal injection
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only
  • EU: Rx-only
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC4318H6788N1164O1304S32
Molar mass96898.57 g·mol−1
 NY (what is this?)  (verify)

It is an inhibitor of vascular endothelial growth factor (VEGF).

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