Adiponectin receptor 1

ADIPOR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3WXV
Identifiers
Aliases	ADIPOR1, adiponectin receptor 1, ACDCR1, CGI45, PAQR1, TESBP1A, CGI-45
External IDs	OMIM: 607945 MGI: 1919924 HomoloGene: 69199 GeneCards: ADIPOR1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	202,958,572 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	134,361,089 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; bone marrow; ; skin of abdomen; ; islet of Langerhans; ; right lung; ; minor salivary gland; ; upper lobe of left lung; ; muscle of leg; ; gastrocnemius muscle;
	Top expressed in
	blood; ; knee joint; ; triceps brachii muscle; ; atrium; ; ankle; ; temporal muscle; ; retinal pigment epithelium; ; vastus lateralis muscle; ; sternocleidomastoid muscle; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	adipokinetic hormone receptor activity; adiponectin binding; metal ion binding; identical protein binding; protein heterodimerization activity; protein kinase binding; signaling receptor activity;
Cellular component	integral component of membrane; membrane; intrinsic component of plasma membrane; plasma membrane;
Biological process	glucose homeostasis; lipid metabolism; leptin-mediated signaling pathway; adiponectin-activated signaling pathway; fatty acid metabolic process; regulation of lipid metabolic process; regulation of glucose metabolic process; negative regulation of cell growth; fatty acid oxidation; hormone-mediated signaling pathway; positive regulation of insulin receptor signaling pathway; positive regulation of receptor signaling pathway via JAK-STAT; negative regulation of epithelial to mesenchymal transition; negative regulation of receptor signaling pathway via JAK-STAT; negative regulation of epithelial cell migration; negative regulation of NIK/NF-kappaB signaling; G protein-coupled receptor signaling pathway; regulation of fatty acid biosynthetic process; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	51094
	72674
	ENSG00000159346
	ENSMUSG00000026457
	Q96A54
	Q91VH1
	NM_001290553; NM_001290557; NM_001290629; NM_015999
	NM_028320; NM_001306069
	NP_001277482; NP_001277486; NP_001277558; NP_057083
	NP_001292998; NP_082596
	Wikidata
View/Edit Human	View/Edit Mouse

Adiponectin receptor 1 (AdipoR1) is a protein which in humans is encoded by the ADIPOR1 gene. It is a member of the progestin and adipoQ receptor (PAQR) family, and is also known as PAQR1.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.