Adenosine A_2B receptor

ADORA2B
Identifiers
Aliases	ADORA2B, ADORA2, adenosine A2b receptor
External IDs	OMIM: 600446 MGI: 99403 HomoloGene: 20167 GeneCards: ADORA2B
Gene location (Human)
Chr.	Chromosome 17 (human)
End	15,975,746 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	62,157,279 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; retinal pigment epithelium; ; skin of abdomen; ; rectum; ; vulva; ; cingulate gyrus; ; monocyte; ; nucleus accumbens; ; caudate nucleus; ; stromal cell of endometrium;
	Top expressed in
	retinal pigment epithelium; ; yolk sac; ; corneal stroma; ; otic placode; ; secondary oocyte; ; urinary bladder; ; jejunum; ; lip; ; sciatic nerve; ; iris;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled adenosine receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; intracellular anatomical structure; synapse; Schaffer collateral - CA1 synapse; glutamatergic synapse;
Biological process	cellular response to extracellular stimulus; positive regulation of chronic inflammatory response to non-antigenic stimulus; G protein-coupled receptor signaling pathway; G protein-coupled adenosine receptor signaling pathway; excretion; positive regulation of guanylate cyclase activity; adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of mast cell degranulation; activation of adenylate cyclase activity; cellular defense response; JNK cascade; positive regulation of interleukin-6 production; relaxation of vascular associated smooth muscle; positive regulation of chemokine production; positive regulation of vascular endothelial growth factor production; signal transduction; positive regulation of cGMP-mediated signaling; regulation of synaptic vesicle exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	136
	11541
	ENSG00000170425
	ENSMUSG00000018500
	P29275
	Q60614
	NM_000676
	NM_007413
	NP_000667
	NP_031439
	Wikidata
View/Edit Human	View/Edit Mouse

The adenosine A_2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human adenosine A_2b receptor gene which encodes it.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

Adenosine A2B receptor

Adenosine A_2B receptor