Acriflavine

Acriflavine (INN: acriflavinium chloride) is a topical antiseptic. It has the form of an orange or brown powder. It may be harmful in the eyes or if inhaled. It is a dye and it stains the skin and may irritate. The hydrochloride form is more irritating than the neutral form. It is derived from acridine. Commercial preparations are often mixtures with proflavine. It is known by a variety of commercial names.

Acriflavine

Sample of pure acriflavine
Names
Preferred IUPAC name
3,6-Diamino-10-methylacridin-10-ium chloride
Other names
Acriflavinium chloride (INN)
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.211.047
EC Number
  • 201-668-8
UNII
  • InChI=1S/C14H13N3.ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;/h2-8H,1H3,(H3,15,16);1H N
    Key: KKAJSJJFBSOMGS-UHFFFAOYSA-N N
  • InChI=1S/C14H13N3.C13H11N3.ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;1H
    Key: PEJLNXHANOHNSU-UHFFFAOYSA-N
  • Key: PEJLNXHANOHNSU-UHFFFAOYSA-N
  • [Cl-].C[N+]1=C2C=C(N)C=CC2=CC2=C1C=C(N)C=C2
  • [Cl-].n1c3c(cc2c1cc(N)cc2)ccc(c3)N.Nc3cc2[n+](c1cc(N)ccc1cc2cc3)C
Properties
C14H14ClN3
Molar mass 259.74 g·mol−1
Pharmacology
R02AA13 (WHO) QG01AC90 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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