ASCL2

ASCL2
Identifiers
Aliases	ASCL2, ASH2, HASH2, MASH2, bHLHa45, achaete-scute family bHLH transcription factor 2
External IDs	OMIM: 601886 MGI: 96920 HomoloGene: 3789 GeneCards: ASCL2
Gene location (Human)
Chr.	Chromosome 11 (human)
End	2,270,588 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	142,523,001 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; monocyte; ; palpebral conjunctiva; ; blood; ; amniotic fluid; ; skin of abdomen; ; jejunal mucosa; ; skin of limb; ; duodenum; ; seminal vesicula;
	Top expressed in
	trophoblasts; ; Paneth cell; ; rib; ; lacrimal gland; ; female urethra; ; basisphenoid; ; human mandible; ; parotid gland; ; duodenum; ; pretectal area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; transcription factor binding;
Cellular component	nucleus; RNA polymerase II transcription regulator complex; cytoplasm;
Biological process	cell differentiation; spongiotrophoblast layer development; response to hypoxia; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; nervous system development; multicellular organism development; regulation of neurogenesis; in utero embryonic development; placenta development; negative regulation of Schwann cell proliferation; somatic stem cell population maintenance; spongiotrophoblast differentiation; sensory organ development; neuron differentiation; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	430
	17173
	ENSG00000183734
	ENSMUSG00000009248
	Q99929
	O35885
	NM_005170
	NM_008554
	NP_005161
	NP_032580
	Wikidata
View/Edit Human	View/Edit Mouse

Achaete-scute complex homolog 2 (Drosophila), also known as ASCL2, is an imprinted human gene.

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