ANP32D

Acidic leucine-rich nuclear phosphoprotein 32 family member D is a protein that in humans is encoded by the ANP32D gene.

ANP32D
Identifiers
AliasesANP32D, PP32R2, acidic nuclear phosphoprotein 32 family member D
External IDsOMIM: 606878 GeneCards: ANP32D
Orthologs
SpeciesHumanMouse
Entrez

23519

n/a

Ensembl

ENSG00000139223

n/a

UniProt

O95626

n/a

RefSeq (mRNA)

NM_012404

n/a

RefSeq (protein)

NP_036536

n/a

Location (UCSC)Chr 12: 48.47 – 48.47 Mbn/a
PubMed searchn/a
Wikidata
View/Edit Human

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns.

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