ALD-52

ALD-52
Clinical data
Other names	1-Acetyl-N,N-diethyllysergamide, ALD, N-acetyl-LSD, Acetyl lysergic acid diethylamide, d-acetyl lysergic acid diethylamide, d-acetyldiethyllysergamide
Routes of; administration	Oral
Legal status
Legal status	AU: Unscheduled; BR: Class F2 (Prohibited psychotropics); CA: Unscheduled; DE: NpSG (Industrial and scientific use only); UK: Class A; US: Unscheduled, could be persecuted under the Federal Analogue Act.; Unscheduled in the most countries of the world, Illegal in France, Romania, Switzerland, Finland and Singapore;
Pharmacokinetic data
Metabolism	hepatic
Excretion	renal
Identifiers
	IUPAC name (6aR,9R)-4-Acetyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide;
CAS Number	3270-02-8 ;
PubChem CID	201111;
ChemSpider	174121 ;
UNII	R224WJZ8M7;
CompTox Dashboard (EPA)	DTXSID20186370 ;
Chemical and physical data
Formula	C22H27N3O2
Molar mass	365.477 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(n1cc2c3c(C4=C[C@@H](C(=O)N(CC)CC)CN([C@@H]4C2)C)cccc13)C;
	InChI InChI=1S/C22H27N3O2/c1-5-24(6-2)22(27)16-10-18-17-8-7-9-19-21(17)15(13-25(19)14(3)26)11-20(18)23(4)12-16/h7-10,13,16,20H,5-6,11-12H2,1-4H3/t16-,20-/m1/s1 ; Key:FJOWXGYLIWJFCH-OXQOHEQNSA-N ;
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ALD-52, also known as 1-acetyl-LSD, has chemical structural features similar to lysergic acid diethylamide (LSD), a known psychedelic drug. Similarly, ALD-52 has been reported to produce psychoactive effects, but its pharmacological effects on humans are poorly understood. Given its psychoactive properties, it has been reported to be consumed as a recreational drug, and the purported first confirmed detection of the substance on the illicit market occurred in April 2016.

ALD-52 was initially synthesized in 1957 by Albert Hofmann, who is accredited as the first individual to have synthesised LSD, a chemical analogue of ALD-52. Until the rise in popularity of psychedelics in the 1960s, ALD-52 was not widely studied. It is assumed to act as a prodrug to LSD in humans, but this has yet to be scientifically verified.

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