AKT1S1

AKT1S1
Identifiers
Aliases	AKT1S1, Lobe, PRAS40, AKT1 substrate 1
External IDs	OMIM: 610221 MGI: 1914855 HomoloGene: 12162 GeneCards: AKT1S1
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,878,459 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,504,845 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; right adrenal gland; ; left adrenal gland; ; gastric mucosa; ; right lobe of liver; ; skin of abdomen; ; body of stomach; ; right coronary artery; ; left ventricle; ; left coronary artery;
	Top expressed in
	yolk sac; ; extensor digitorum longus muscle; ; knee joint; ; molar; ; lip; ; vastus lateralis muscle; ; atrium; ; esophagus; ; plantaris muscle; ; triceps brachii muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	TORC1 complex; nucleus; nucleoplasm; cytoplasm; cytosol; protein-containing complex;
Biological process	regulation of cellular response to heat; negative regulation of TOR signaling; regulation of neuron apoptotic process; negative regulation of protein kinase activity; negative regulation of cell size; neurotrophin TRK receptor signaling pathway; TORC1 signaling; regulation of apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	84335
	67605
	ENSG00000204673
	ENSMUSG00000011096
	Q96B36
	Q9D1F4
	NM_032375; NM_001098632; NM_001098633; NM_001278159; NM_001278160
NM_001253920; NM_001290694; NM_001290695; NM_026270; NM_001382480;
	NM_001382481; NM_001382482; NM_001382483; NM_001382484
	NP_001092102; NP_001092103; NP_001265088; NP_001265089; NP_115751
NP_001240849; NP_001277623; NP_001277624; NP_080546; NP_001369409;
	NP_001369410; NP_001369411; NP_001369412; NP_001369413
	Wikidata
View/Edit Human	View/Edit Mouse

Proline-rich AKT1 substrate 1 (PRAS) is a protein that in humans is encoded by the AKT1S1 gene.

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