ADAMTS1

ADAMTS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JIH, 2V4B, 3Q2G, 3Q2H
Identifiers
Aliases	ADAMTS1, C3-C5, METH1, ADAM metallopeptidase with thrombospondin type 1 motif 1
External IDs	OMIM: 605174 MGI: 109249 HomoloGene: 21381 GeneCards: ADAMTS1
Gene location (Human)
Chr.	Chromosome 21 (human)
End	26,845,409 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	85,600,001 bp
RNA expression pattern
	Top expressed in
	left uterine tube; ; vena cava; ; pericardium; ; gastric mucosa; ; mucosa of urinary bladder; ; ascending aorta; ; left coronary artery; ; gallbladder; ; smooth muscle tissue; ; saphenous vein;
	Top expressed in
	iris; ; left lung lobe; ; ciliary body; ; ascending aorta; ; aortic valve; ; vas deferens; ; uterus; ; belly cord; ; dermis; ; atrioventricular valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	heparin binding; zinc ion binding; metal ion binding; peptidase activity; metalloendopeptidase activity; hydrolase activity; metallopeptidase activity;
Cellular component	extracellular region; basement membrane; cytoplasmic vesicle; extracellular matrix; collagen-containing extracellular matrix;
Biological process	ovulation from ovarian follicle; heart trabecula formation; kidney development; proteolysis; integrin-mediated signaling pathway; negative regulation of cell population proliferation; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of vascular associated smooth muscle cell proliferation; positive regulation of vascular associated smooth muscle cell migration;
	Sources:Amigo / QuickGO
Orthologs
	9510
	11504
	ENSG00000154734
	ENSMUSG00000022893
	Q9UHI8
	P97857
	NM_006988
	NM_009621
	NP_008919
	NP_033751
	Wikidata
View/Edit Human	View/Edit Mouse

A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.