2022 U.S. Open Cup

The 2022 Lamar Hunt U.S. Open Cup was the 107th edition of the U.S. Open Cup, a knockout cup competition in American soccer. After the 2020 and 2021 competitions were suspended and ultimately canceled due to the COVID-19 pandemic, the United States Soccer Federation announced that the 2022 edition would run from March to mid-September of that year. The 2022 field features 103 clubs, 71 of them fully professional—both modern-era records.

On December 22, 2021, U.S. Soccer announced the final format for the 2022 tournament, with two major changes from prior editions. First, all eligible Division II and Division III professional teams will enter in the second round. Second, Major League Soccer will have its entry staggered: Seventeen MLS teams will enter in the Third Round, and the remaining eight teams (the four playing in the 2022 CONCACAF Champions League, and the next highest two teams in both the Eastern and Western Conferences) will enter in the Round of 32.

For the first time since 2017, multiple leagues from the same division competed in the Open Cup. USL League One, of Division III, competed alongside teams from MLS Next Pro and the National Independent Soccer Association (NISA). NISA was set to make its Open Cup debut in 2020, before that tournament was canceled; MLS Next Pro was established in 2021, and while primarily a developmental league for MLS teams, its independent clubs are eligible for the Open Cup.

Atlanta United FC were the defending champions, having won the 2019 tournament, but were eliminated in the Round of 32 by Nashville SC.

Orlando City SC won their first Open Cup title, defeating Sacramento Republic FC 3–0 in the final.