α-Ketoglutaric acid

α-Ketoglutaric acid
Names
	Preferred IUPAC name 2-Oxopentanedioic acid
	Other names 2-Ketoglutaric acid; alpha-Ketoglutaric acid; 2-Oxoglutaric acid; Oxoglutaric acid
Identifiers
CAS Number	328-50-7 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:30915 ;
ChemSpider	50 ;
DrugBank	DB02926 ;
ECHA InfoCard	100.005.756
IUPHAR/BPS	3636;
KEGG	C00026 ;
MeSH	alpha-ketoglutaric+acid
PubChem CID	51;
UNII	8ID597Z82X ;
CompTox Dashboard (EPA)	DTXSID5033179 ;
	InChI InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10) Key: KPGXRSRHYNQIFN-UHFFFAOYSA-N ; InChI=1/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10) Key: KPGXRSRHYNQIFN-UHFFFAOYAN;
	SMILES O=C(O)C(=O)CCC(=O)O;
Properties
Chemical formula	C5H6O5
Molar mass	146.098 g·mol−1
Melting point	115 °C (239 °F; 388 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

α-Ketoglutaric acid (2-oxoglutaric acid) is a keto acid.

Its carboxylate, α-ketoglutarate (also called 2-oxoglutarate), is an important biological compound. It is produced by deamination of glutamate, and is an intermediate in the Krebs cycle.

The term "ketoglutaric acid," when not further qualified, almost always refers to the alpha variant. β-Ketoglutaric acid varies only by the position of the ketone functional group, and is much less common.

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